What is a biosafety cabinet (BSC), and when is it used?

• A. A BSC provides personnel, product, and environmental protection when handling infectious or hazardous biological materials; used for tissue culture, open handling of pathogens, and aerosol-generating procedures.
• B. A BSC is a chemical fume hood used for heating solvents.
• C. A BSC is a storage cabinet for biospecimens.
• D. A BSC is a centrifuge used for separating cells.

Answer: (A)

A biosafety cabinet is a specialized containment device that protects personnel, the product, and the environment when working with infectious or hazardous biological materials. It uses HEPA-filtered airflow to pull clean air across the work surface and exhaust air away from the user, reducing exposure and preventing contamination. It is used for tissue culture, open handling of pathogens, and procedures that generate aerosols. It is not a chemical fume hood used for solvents, not a storage cabinet, and not a centrifuge.